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地塞米松过夜抑制加测午夜12时值试验,是观察血浆皮质醇值的生理节律变化及其反馈调节机制,了解下丘脑—垂体—肾上腺皮质轴功能状态的一种简便、有效的方法。对于某些内分泌疾病的诊断和治疗具有重要价值。近年来,我们采用放射免疫分析法,测定了73例正常成人对该试验的反应。其结果如下:
Overnight inhibition of dexamethasone plus test of midnight 12 o’clock is a simple and effective way to observe the circadian rhythm of plasma cortisol and its feedback regulation mechanism to understand the functional status of the hypothalamus-pituitary-adrenal axis. For some endocrine disease diagnosis and treatment of great value. In recent years, we used radioimmunoassay to determine the response of 73 normal adults to this trial. The result is as follows: