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自从奎宁不再用于疟疾的化学预防以来,黑水热、急性血管内溶血几乎消失。但卤泛曲林的结构与奎宁相似,而且广泛地用于疟疾的假定性治疗和临床性治疗。本文报告1例因恶性疟发作用卤泛曲林治疗后出现的血管内溶血。该病人曾有以奎宁作假定性治疗史。
Since quinine is no longer used for chemical prevention of malaria, black-hot water and acute intravascular hemolysis almost disappear. However, halibutramine is similar in structure to quinine and is widely used in the presumptive and clinical treatment of malaria. This article reports one case of intravascular hemolysis after treatment with halibutramine due to falciparum malaria. The patient had a history of quinine as a suppositional treatment.