本实验以高效液相色谱-电化学检测器法测定正常足月新生儿交感神经系统活性,并探索其在休克时的变化,以期指导临床休克的早期诊断。结果表明,新生儿交感神经系统活性已发育达一定水平,可以对休克产生反应,新生儿休克早期可无血压下降征象。另外,对一些临床指标的观察发现,肛温、肛-腋温差、毛细血管充盈时间是休克早期较有效的监测指标。 In this study, the normal full-term neonatal sympathetic nervous system activity was measured by high performance liquid chromatography-electrochemical detector and its changes in shock were explored in order to guide the early diagnosis of clinical shock. The results show that the neonatal sympathetic nervous system activity has been developed to a certain level, can respond to shock, early neonatal shock can be no signs of blood pressure. In addition, the observation of some clinical indicators found that the rectal temperature, anus - axillary temperature difference, capillary filling time is more effective in the early monitoring of shock indicators.