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周围血干细胞移植术(PBSCT)使淋巴瘤的治疗成绩有了明显提高。周围血干细胞的提取(PBSCH),一般是用大量环磷酰胺或ETP疗法后,再用G-CSF,在骨髓造血功能恢复期,干细胞从骨髓动员至外周血进行提取而成。然而,为进行PBSCT用频繁的巩固化疗必定影响干细胞的提取。作者用ABVD+G-CSF方案,对复发的、预后不良的高危性霍奇金淋巴瘤(HD)不改变原治疗计划的基层上,探讨提取PBSCT的可能性。方法:1.周围血干细胞的
Peripheral blood stem cell transplantation (PBSCT) has significantly improved the treatment of lymphoma. Peripheral blood stem cell extraction (PBSCH) is usually followed by a large amount of cyclophosphamide or ETP therapy followed by G-CSF. In the hematopoietic recovery period of bone marrow, stem cells are mobilized from bone marrow to peripheral blood for extraction. However, frequent consolidation chemotherapy for PBSCT will definitely affect stem cell extraction. The authors used the ABVD+G-CSF regimen to explore the possibility of retrieving PBSCT on relapsed, poor-prognosed high-risk Hodgkin’s lymphoma (HD) without changing the original treatment plan. Methods: 1. Peripheral blood stem cells