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目的:研究肺宁片对感冒后咳嗽患者血清Th1/Th2细胞因子的影响。方法:分析了2015年2月—2015年6月辽宁中医药大学附属第二医院呼吸科、急诊科收治的20例患者的临床资料。采用Legend Plex多因子定量分析法(Bio Legend Legend Plex?)分别检测20例患者给药前(A组)、给药后(B组)血清细胞因子的表达水平。结果:给药前后两组患者的IFN-γ水平差异具有统计学意义(P<0.05),IL-4表达虽有降低趋势,但差异无统计学意义。结论:肺宁片治疗感冒后咳嗽,可能与Th1/Th2细胞因子平衡有关。
Objective: To investigate the effect of Feining tablet on serum Th1 / Th2 cytokines in patients with cough after cold. Methods: The clinical data of 20 patients admitted to Department of Respiratory and Emergency Medicine, Second Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from February 2015 to June 2015 were analyzed. The levels of serum cytokines in 20 patients before administration (group A) and after administration (group B) were determined by the Legend Plex multi-factor quantitative analysis (Bio-Legend Legend Plex?). Results: The levels of IFN-γ in the two groups before and after treatment had statistical significance (P <0.05), while the expression of IL-4 showed a decreasing trend, but the difference was not statistically significant. Conclusion: The treatment of cough by Minning tablet in cold may be related to the balance of Th1 / Th2 cytokines.