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随着对脊椎肌萎缩症（ＳＭＲ）相关基因，即生存运动神经元（ＳＭＮ）和神经元细胞凋亡抑制蛋白（ＮＡＩＰ）二基因的认识，１９９５年，人们对脊椎肌萎缩症的分子病理学有了进一步了解。ＳＭＮ和ＮＡＩＰ这两个基因在５ｐ１３处存在多重拷贝（ＳＭＮＴ）的纯合缺失，而大多
With the recognition of genes related to spondylolisthesis (SMR), namely Surviving motor neurons (SMN) and Neuronal Apoptosis Inhibiting Protein (NAIP), the molecular pathology of spondyloarthropathy Have a better understanding. The two genes SMN and NAIP present homozygous deletion of multiple copies (SMN-T) at 5p13, whereas most