冷冻外科已被成功地应用于治疗口腔软硬组织肿瘤。但是,它同其他的治疗方法一样,可以引起不良的后遗症:如瘢痕形成、功能损害、创口愈合时间延长、牙槽骨暴露、病理性骨折、顽固性淋巴结肿大以及放射性骨坏死(曾做过放射治疗的病例)。在应用冷冻外科治疗前,应仔细考虑这些后遗症对患者的影响。创口愈合的时期和瘢痕形成冷冻外科的创口为二期愈合。冷冻区经历坏死和腐肉脱离,其深面的肉芽组织床最终形成纤维性瘢痕组织。创口愈合的时期及瘢痕组织形成的量取决于冷冻的面积和冷冻的程度。充分地治疗口底或舌侧的T_1肿瘤时,软组织创口愈合时期一般需4—8周。伴发的瘢痕可以明显地改变冷冻区的解剖结构。舌前庭深度的丧失可以造成将来作全口 Cryosurgery has been successfully used to treat oral and soft tissue tumors. However, as with other treatments, it can cause undesirable sequelae such as scarring, impaired function, prolonged wound healing, alveolar bone exposure, pathologic fractures, refractory lymph nodes, and osteonecrosis of the bone Radiation therapy cases). Before applying cryosurgical treatment, the effects of these sequelae on the patient should be carefully considered. Wound healing period and scar formation Frozen surgical wounds are second-stage healing. The frozen zone undergoes necrosis and carcass detachment, and the deep granulation tissue bed eventually forms fibrous scar tissue. The period of wound healing and the formation of scar tissue depend on the area of ​​the frozen area and the degree of freezing. When adequately treating T_1 tumors in the mouth or the lingual, the soft tissue wound healing period typically takes 4-8 weeks. Concomitant scarring can significantly alter the anatomy of the frozen area. The loss of the depth of the vestibule can make the whole mouth full