地塞米松磷酸钠(简称D)注射液的含量测定,中国药典采用异烟肼比色法,该法繁琐、耗时,且重现性较差。鉴于目前以丙二醇代替烟酰胺作为该药的稳定剂(本刊,1985,16:330),不致发生烟酰胺在242nm 处对测定的干扰现象,可直接进行紫外测定,吸收度与浓度呈线性关系,回收率达100.57％,方法简便、快速、准确,适用于产品、中间产品的 Determination of dexamethasone sodium phosphate (referred to as D) injection, Chinese Pharmacopoeia using isoniazid colorimetric method, the method cumbersome, time-consuming, and poor reproducibility. In view of the current propylene glycol instead of nicotinamide as a stabilizer of the drug (Articles, 1985,16: 330), nicotinamide does not occur at 242nm interfere with the determination of the phenomenon can be directly measured by UV, the absorption was linear with the concentration , The recovery rate of 100.57%, the method is simple, fast, accurate, suitable for products, intermediate products