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糖尿病病人脂代谢紊乱是导致伴发冠心病的重要因素。近年来国内外的一些研究发现,冠心病病人及NIDDM病人血清中HDL-C,HDL_2-C、HDL_3-C均降低,其中以HDL_2-C下降明显;低密度脂蛋白胆固醇(LDL-C)和ApoB则增高。由于脂蛋白胆固醇受糖尿病类型、性别、年龄、月经周期的影响表现出很大差异,本文选择了一组女性绝经后NIDDM病人与相应正常人比较,以了解该组病人胆固醇代谢紊乱与冠心病的关系,并探讨了测定血清脂蛋白胆固醇以及ApoB对评估该组NIDDM病人冠心病的价值。
Diabetic patients with lipid metabolism disorder is an important factor leading to coronary heart disease. In recent years, some studies at home and abroad found that serum HDL-C, HDL-C and HDL-3-C were decreased in patients with coronary heart disease and NIDDM patients, especially HDL-C, while LDL- ApoB is higher. Because of lipoprotein cholesterol by the type of diabetes, sex, age, menstrual cycle, the impact of significant differences, this paper chose a group of women with postmenopausal NIDDM patients with the corresponding normal, in order to understand the group of patients with metabolic disorders and coronary heart disease And to explore the determination of serum lipoprotein cholesterol and ApoB to assess the value of this group of patients with coronary heart disease NIDDM.