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目的:探索良好的肠吻合术式,以防止肠闭锁之小口径肠管吻合术后吻合口梗阻的发生。方法:改良肠单层吻合术与全层内翻吻合术进行动物实验比较,并临床应用。结果:切片观察示吻合口粘膜连续性恢复好,粘膜缺损少,粘膜下移少而轻,粘膜下层对合满意。与全层内翻吻合比较有统计学差异。术后2周吻合口标本羟脯氨酸含量(代表胶原含量)实验组与对照组分别为43.527μg/mg 干重和41.423μg/mg 干重(P>0.05)。7例肠闭锁患儿手术效果满意。结论:改良肠单层吻合术不仅简便省时,而且有利于吻合口愈合,防止吻合口梗阻发生,尤其适用于小口径肠管。
Objective: To explore a good type of intestinal anastomosis to prevent the occurrence of anastomotic obstruction after small bowel anastomosis of intestinal atresia. Methods: An improved intestinal single-layer anastomosis and full-thickness anastomosis for animal experiments, and clinical application. Results: Slices showed good anastomotic mucosal continuity recovery, less mucosal defects, less and less submucosal shift, satisfaction with submucosa. Compared with full-thickness endovascular anastomosis statistically significant. The content of hydroxyproline (representative of collagen content) in experimental group and control group at 2 weeks after operation were 43.527μg / mg dry weight and 41.423μg / mg dry weight respectively (P> 0.05). 7 cases of intestinal obstruction in children with satisfactory results. Conclusion: Improved single intestinal anastomosis is not only simple and time-saving, but also conducive to anastomotic healing, to prevent anastomotic obstruction occurs, especially for small-caliber intestinal.