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目的探讨缬沙坦联合前列地尔治疗糖尿病肾病(DN)的临床效果。方法选取90例DN患者,随机分为两组,均给予常规治疗,对照组患者在常规治疗的基础上给予前列地尔注射液治疗,治疗组患者在常规治疗基础上给予前列地尔注射液+缬沙坦胶囊口服治疗,比较两组患者的治疗效果。结果经2个疗程治疗后,治疗组患者总有效率为91.1%,明显高于对照组的77.8%,差异有统计学意义(P<0.05)。结论缬沙坦联合前列地尔治疗糖尿病肾病效果理想。
Objective To investigate the clinical effect of valsartan and alprostadil on diabetic nephropathy (DN). Methods Ninety patients with DN were randomly divided into two groups. All patients in the control group were given conventional therapy. Patients in the control group were treated with alprostadil injection on the basis of routine treatment. The patients in the treatment group were given alprostadil injection + Valsartan capsules oral treatment, the treatment effect of two groups of patients were compared. Results After 2 courses of treatment, the total effective rate of the treatment group was 91.1%, which was significantly higher than that of the control group (77.8%), the difference was statistically significant (P <0.05). Conclusion Valsartan combined with alprostadil is effective in treating diabetic nephropathy.