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报告130份供血者血瓶血的检测,及124例受血者的随访结果。HBIG 组63例,接受 HBV-DNA 阳性血7份,输血后无1例阳转;接受抗-HBc 阳性血3份,输血后阳转1例。阳转率1/10。对照组61例,接受抗-HBc 阳性血6份,输血后抗-HBc 转阳2例,SGPT 升高伴有纳差,乏力等症状者1例。阳性率为3/6。另外,接受 HBV 标志均阴性的血液,HBIG 组53例,1例 SGPT 升高。对照组55例,2例 HBV-DNA 转阳,3例 SGPT 升高。初步探讨抗-HBc 低滴度阳性的临床意义及传染性问题,对今后 HBIG 预防方法提出了改进意见。
A total of 130 blood donor blood tests were reported, followed by 124 blood recipients. In HBIG group, 63 cases were positive for HBV-DNA, 7 cases were positive for HBV-DNA, 1 case was positive after transfusion; 3 cases were positive for anti-HBc, and 1 case was positive after blood transfusion. Positive conversion rate 1/10. The control group of 61 patients received 6 anti-HBc positive blood transfusion after anti-HBc positive in 2 cases, SGPT increased with anorexia, fatigue and other symptoms in 1 case. The positive rate of 3/6. In addition, patients receiving HBV markers were negative in the blood, HBIG group of 53 cases, 1 case of SGPT increased. The control group, 55 cases, 2 cases of HBV-DNA turn positive, 3 cases of SGPT increased. Preliminary study of anti-HBc positive low-titer clinical significance and infectious problems, the prevention of HBIG in the future proposed improvements.