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目的:观察祛瘀降浊法治疗急性脑卒中后急性肾损伤(AKI)的疗效。方法:选取本院2014年12月至2015年12月收治的44例急性脑卒中后并发AKI患者作为研究对象,应用随机双盲法将患者分为观察组与对照组,对照组患者予以西医常规治疗,观察组患者在对照组治疗基础上应用祛瘀降浊法治疗,观察两组患者治疗前后血清肌酐水平、临床疗效及不良反应情况。结果:对照组治疗总有效率为81.81%,总不良反应率为22.73%,观察组治疗总有效率95.45%、总不良反应率4.55%,观察组总有效率显著高于对照组,总不良反应率明显低于对照组,且观察组治疗后平均血清肌酐水平较对照组明显降低,均差异具有统计学意义(P<0.05)。结论:应用祛瘀降浊法治疗急性脑卒中后并发AKI的疗效显著,患者症状改善明显,不良反应少,安全性高。
Objective: To observe the curative effect of removing blood stasis and lowering turbidity on acute renal injury (AKI) after acute stroke. Methods: Forty-four patients with AKI complicated with acute stroke who were treated in our hospital from December 2014 to December 2015 were selected as study subjects. Patients were divided into observation group and control group by randomized double-blind method. Patients in control group were treated with routine western medicine The patients in the observation group were treated with the method of removing blood stasis and lowering turbidity on the basis of the treatment of the control group. The levels of serum creatinine, clinical efficacy and adverse reactions in the two groups were observed before and after treatment. Results: The total effective rate of the control group was 81.81%, the total adverse reaction rate was 22.73%. The total effective rate of the observation group was 95.45%, the total adverse reaction rate was 4.55%. The total effective rate of the observation group was significantly higher than that of the control group. The total adverse reactions The mean serum creatinine level in the observation group was significantly lower than that in the control group, with statistical significance (P <0.05). Conclusion: The treatment of acute stroke with AKI is effective in removing blood stasis and resolving turbidity. The symptoms of the patients are obviously improved with fewer adverse reactions and high safety.