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我院对近年来经临床及病理诊断葡萄胎183例进行了预防性化厅,1次刮宫51例,2次刮宫58例,3次刮宫42例.预防性子宫切除32例.3次刮宫是根据2次刮宫病理报告,有滋养细胞增生,伴有血HCG增高,刮宫术后仍有阴道不规则流血。183例中36例单用5Fu20～25mg/kg·d静点。10天为一疗程,间隔2—4周;16例单用KSM6～8μg/kg·d静点,10天为一疗程,间隔2—4周;有高危因素14例用5Fu25～30mg/kg·d及KSM 8μg/kg·d交替静点,10天为一疗程:其余患者用5Fu及KSM以单用药剂量交替使用,8天为一疗程.化疗次数是根据血HCG水平及刮官
In our hospital, 183 cases of hydatidiform moles were clinically and pathologically diagnosed in recent years, and preventive clinics were conducted. There were 51 cases of curettage, 58 cases of curettage, and 42 cases of curettage in 3 cases. Prophylactic hysterectomy was performed in 32 cases. The curettage was 3 times. According to the secondary curettage pathology report, trophoblastic hyperplasia was accompanied by increased blood HCG and irregular vaginal bleeding after curettage. Of the 183 patients, 36 were treated with 5Fu 20-25 mg/kg·d alone. 10 days for a course of treatment, interval 2-4 weeks; 16 cases with KSM6 ~ 8μg/kg · d static point, 10 days for a course of treatment, interval 2-4 weeks; there are 14 high risk factors with 5Fu25 ~ 30mg/kg · d and KSM 8μg/kg·d alternate static point, 10 days for a course of treatment: the remaining patients were alternately used with 5Fu and KSM in a single dose, 8 days for a course of treatment. The number of chemotherapy is based on blood HCG levels and scraping