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肺间质充填于肺泡上皮和毛细血管内皮之间的间隙;也可见于围绕较大血管和气道血管处,支气管周围间隙,以及小叶的间隔。由上皮和内皮层基膜及胶原纤维所组成。肺间质性疾病即指累及肺饱壁和肺饱间隔,以及支气管壁及其周围组织的病变。成年人中以慢性支气管炎、支气管扩张、结节病、胶原性疾病、外源性肺泡炎、弥漫性间质纤维化等为多见。尽管致病因素各不相同,病程长短不一,临床症状也有轻重,但发生的后果一致,其发病机理如图所示。
Interstitial lung interstitial filling in the gap between the alveolar epithelium and capillary endothelium; also found in the larger vessels and airways around the vessel, the bronchial space, and the leaflet interval. By the epithelial and endodermis basement membrane and collagen fibers. Pulmonary interstitial disease refers to involving the fullness of the lung and satiety of the lungs, as well as the bronchial wall and its surrounding tissue lesions. Adults with chronic bronchitis, bronchiectasis, sarcoidosis, collagen disease, exogenous alveolitis, diffuse interstitial fibrosis are more common. Although the pathogenic factors vary, duration of the disease, clinical symptoms are also serious, but the consequences of the same, the pathogenesis as shown.