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目的:探讨280例胃食管反流病(GERD)的分布特点及危险因素。方法:对临床诊断和胃镜确诊的280例GERD患者进行临床和风险因子相关性分析。结果:不论汉族还是维族,男性患者比例均明显高于女性;汉族患者高发年龄段早于维族患者(Z=-2.939,P=0.003,);汉族和维族患者占反流性食管炎和Barrett食管比例分别为42.4%、81.3%及56.5%、18.8%,其中汉族患者Barrett食管比例较高(X2=14.358,P=0.000);肥胖、习惯性便秘、重体力活动者、饮食习惯不良在维族患者中的比例较高(P<0.001)。结论:GERD与性别、年龄密切相关,男性多于女性,汉族患者发病年龄高峰早于维族患者;汉族患者Barrett食管发生比例高于维族患者;肥胖、习惯性便秘、重体力活动、饮食习惯不良可能是GERD尤其是维族人群GERD的危险因素。
Objective: To investigate the distribution and risk factors of 280 cases of gastroesophageal reflux disease (GERD). Methods: Clinical and risk factors were analyzed in 280 GERD patients diagnosed by endoscopy and endoscopy. Results: The proportion of male patients in both Han and Uygur nationality groups was significantly higher than that of female patients. Han nationality patients were predominantly older than Uygur nationality patients (Z = -2.939, P = 0.003, P = 0.003); Han and Uighur patients accounted for reflux esophagitis and Barrett’s esophagus (42.4%, 81.3%, 56.5% and 18.8% respectively), of which Barrett’s esophagus was higher in Han patients (X2 = 14.358, P = 0.000); obesity, habitual constipation, heavy physical activity, In the higher proportion (P <0.001). Conclusions: GERD is closely related to gender and age, and there are more males than females. The age of onset of Han patients is earlier than that of Uygur patients. The incidence of Barrett’s esophagus in Han patients is higher than that of Uyghur patients. Obesity, habitual constipation, heavy physical activity and poor eating habits may be Is a risk factor for GERD, especially in Uygur population.