心力衰竭是指在静脉回流正常情况下,由于原发性心肌损害引起的心排血量减少,不能满足组织代谢需要的一种综合征。其诊断依赖于临床症状及体征、胸部X线片、心电图、血细胞计数等。目前对心力衰竭诊断及治疗的血清标志物研究较多,主要包括钠尿肽类、强心类固醇、细胞因子、肾上腺髓质素、瘦素及肌钙蛋白等。这些标志物在心力衰竭的诊断和治疗中具有各自的特点。该文主要综述了钠尿肽类在心力衰竭诊断和治疗中的作用及应注意的问题。 Heart failure refers to the normal venous return, due to primary cardiac damage caused by decreased cardiac output, can not meet the needs of a metabolic syndrome. The diagnosis depends on clinical symptoms and signs, chest X-ray, electrocardiogram, blood cell count and so on. At present, there are many serum markers for the diagnosis and treatment of heart failure, including natriuretic peptides, cardiac steroids, cytokines, adrenomedullin, leptin and troponin. These markers have their own characteristics in the diagnosis and treatment of heart failure. This article reviews the role of natriuretic peptides in the diagnosis and treatment of heart failure and the problems to be noted.