白血病是一种恶性血液病,又称“血癌”。主要侵犯儿童及青壮年,病死率甚高。四十年代以前人们对此病束手无策。50年代开始使用激素及抗代谢性药物(抗叶酸及抗嘌呤类),少数病人获缓解。自六十年代长春新碱,阿糖胞苷、门冬酰胺酶等药物问世以来,尤其近十年来联合化疗的应用,使白血病预后有了很大改观,小儿急性白血病完全缓解率已显著提高,生存期明显延长。但成人白血病的缓解率及生存期则较儿 Leukemia is a hematological malignancy, also known as “blood cancer.” The main violations of children and young adults, high mortality. By the 1940s people were at a loss what to do with the disease. In the 1950s, hormones and antimetabolites (antifolates and antipurines) were used, and a few patients were relieved. Since the advent of vincristine, cytarabine, asparaginase and other drugs in the 1960s, especially the application of combined chemotherapy in the past decade, the prognosis of leukemia has been greatly improved. The complete remission rate of childhood acute leukemia has been significantly improved, Survival was significantly prolonged. However, the rate of remission and survival of adult leukemia is more children