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目的观察疏风解毒胶囊治疗糖尿病合并肺部感染的临床疗效。方法将223例糖尿病合并肺部感染患者随机分为对照组(120例)和治疗组(103例)。对照组给予常规抗生素治疗,治疗组给予抗生素联合疏风解毒胶囊治疗。两组疗程均为14天,观察生存率、体温、血糖(BG)、血酮、血清丙氨酸氨基转移酶(ALT)、门冬氨酸氨基转移酶(AST)、肌酐(Cr)、C反应蛋白(CRP)、乳酸、降钙素原(PCT)、氧合指数的变化情况。结果 1治疗组生存率为96.1%,对照组为97.5%,两组生存率无显著性差异(P>0.05)。2治疗组体温控制、血糖异常升高、血酮阳性率、ALT、AST、Cr、CRP、乳酸、PCT改善较对照组明显(P<0.05,P<0.01)。3治疗组氧合指数较对照组高(P<0.05)。结论疏风解毒胶囊有助于控制糖尿病合并肺部感染的炎症反应,提高氧和指数。
Objective To observe the clinical efficacy of Shufeng Jiedu Capsule in the treatment of diabetic patients with pulmonary infection. Methods Totally 223 patients with diabetes mellitus and pulmonary infection were randomly divided into control group (120 cases) and treatment group (103 cases). The control group was given routine antibiotic treatment, and the treatment group was given antibiotics combined with Shufeng Jiedu capsule treatment. The duration of treatment was 14 days. The survival rates, body temperature, blood glucose (BG), serum creatinine, serum ALT, AST, creatinine Reactive protein (CRP), lactate, procalcitonin (PCT), oxygenation index changes. Results 1 The survival rate of the treatment group was 96.1%, while that of the control group was 97.5%. There was no significant difference between the two groups (P> 0.05). 2 treatment group, body temperature control, abnormal blood glucose, blood ketone positive rate, ALT, AST, Cr, CRP, lactate, PCT improvement than the control group was significantly (P <0.05, P <0.01). 3 treatment group oxygenation index than the control group (P <0.05). Conclusion Shufeng Jiedu capsule helps to control the inflammatory response of diabetic patients with pulmonary infection and improve the oxygen and index.