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目的:探讨奥美拉唑联合枸橼酸莫沙必利治疗胃食管反流病的临床效果。方法:选取1995年1月至2015年8月本院治疗的确诊胃食管反流病患者64例,随机分为治疗组和对照组各32例,比较两组治疗的临床效果。结果:治疗8周后,治疗组总有效率96.8%,明显优于对照组的84.4%,差异有统计学意义(P<0.05)。治疗组无严重不良反应,对照组有两例治疗过程中出现胸闷不适,停药后好转。结论:奥美拉唑联合枸橼酸莫沙必利治疗胃食管反流病临床有效,值得推广。
Objective: To investigate the clinical effects of omeprazole and mosapride citrate in the treatment of gastroesophageal reflux disease. Methods: Sixty-four patients with confirmed gastroesophageal reflux disease treated in our hospital from January 1995 to August 2015 were randomly divided into treatment group (32 cases) and control group (32 cases). The clinical effects of two groups were compared. Results: After 8 weeks of treatment, the total effective rate of the treatment group was 96.8%, which was significantly better than that of the control group (84.4%), the difference was statistically significant (P <0.05). The treatment group without serious adverse reactions, the control group had two cases of chest tightness and discomfort during treatment, after stopping the improvement. Conclusion: Omeprazole combined with mosapride citrate in the treatment of gastroesophageal reflux disease is clinically effective and worth promoting.