多发性硬化（ｍｕｌｔｉｐｌｅｓｃｌｅｒｏｓｉｓ，ＭＳ）是中枢神经系统脱髓鞘疾病。多见于青年女性。有人报道最小年龄２４个月，１０岁以前发病极少见，不足ＭＳ总数的３‰［１］。因其危害性较大，在儿科领域已引起重视。本文总结了２０例小儿ＭＳ的临床及ＭＲＩ资料，并 Multiple sclerosis (MS) is a demyelinating disease of the central nervous system. More common in young women. It was reported that the youngest age of 24 months, 10 years before the onset of rare, less than 3 ‰ of the total number of MS [1]. Because of its harmfulness, it has drawn great attention in the field of pediatrics. This article summarizes the 20 cases of pediatric MS clinical and MRI data