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近些年来,临床上已采用吸入较大剂量皮质类固醇的方法,尤其是使用丁地去炎松(Budesonide 是一种合成非卤化皮质类固醇,它的局部抗炎作用大于全身性作用),但大剂量二丙氯地米松(BDP)的治疗方法亦仍在应用。作者旨在确定吸入小剂量(400μg/d)和大剂量(1600μg/d)丁地去炎松应用于严重哮喘的疗效并观察是否存在剂量-反应相互联系。
In recent years, clinically the method of inhaling larger doses of corticosteroids has been used clinically, in particular budesonide (Budesonide is a synthetic non-halogenated corticosteroid whose local anti-inflammatory effect is greater than systemic) but large The dose of diproplipodimethasone (BDP) is still being used. The aim of the study was to determine the efficacy of triamcinolone acetonide for small asthma inhalation (400 μg / d) and high dose (1600 μg / d) for severe asthma and to see if there is a dose-response relationship.