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目的：探讨纤维支气管镜导管介入对重症肺结核的治疗价值；方法：６２例重症肺结核住院患者随机分为治疗组３２例及对照组３０例。两组均给于常规治疗，即口服及静脉抗结核化疗加用扩血管药及免疫制剂，合并感染者用抗生素。治疗组经纤维支气管镜导管介入病灶内注入抗结核药。对比观察两组疗效；结果：治疗组退热率１００％、呼吸衰竭治愈率１００％、痰菌阴转率８８％、病灶显效率８４％及空洞有效率７７％，均显著高于对照组的２５％、６７％、５２％、５３％及５２％（Ｐ＜０．０１～０．０５）。治疗组无死亡病例，对照组死亡６例，治疗组病死率显著低于对照组（Ｐ＜０．０５）；结论：纤维支气管镜导管介入病灶内注药加常规治疗重症肺结核，疗效优于常规治疗，尤其在退热及纠正呼吸衰竭方面疗效快而显著
Objective: To investigate the value of bronchofibroscope catheterization for the treatment of severe pulmonary tuberculosis. Methods: Sixty-two patients with severe tuberculosis admitted to hospital were randomly divided into treatment group (n = 32) and control group (n = 30). Both groups were given conventional treatment, namely oral and intravenous anti-TB chemotherapy plus vasodilators and immune agents, with antibiotics. The treatment group was infused with anti-TB drugs through the bronchoscope catheter. The curative effect of the two groups were compared. The results showed that the treatment group had a rate of 100%, the cure rate of respiratory failure was 100%, the sputum negative conversion rate was 88%, the effective rate of the lesions was 84% and the cavity effective rate was 77% 25%, 67%, 52%, 53%, and 52% (P <0.01 ~ 0.05). There were no deaths in the treatment group and 6 deaths in the control group. The mortality rate in the treatment group was significantly lower than that in the control group (P <0.05). Conclusion: The treatment with bronchoscopy with catheterization and conventional treatment of severe pulmonary tuberculosis has better curative effect than conventional Treatment, especially in the fever and correct respiratory failure, rapid and significant effect