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[目的]了解脑转移瘤患者全脑放疗后前瞻性记忆(PM)与回顾性记忆(RM)的功能损害情况。[方法]以34例脑转移瘤患者为研究对象,在全脑放疗前1周、放疗后1个月分别进行简易精神状态量表(MMSE)测查及RM和PM问卷调查。[结果]放疗前后MMSE评分(27.26±1.86 vs 26.35±1.76)差异具有统计学意义(P<0.05)。放疗后PM成绩为12.18±2.74,低于放疗前(14.06±4.66)(P<0.01);RM成绩放疗前后(14.26±4.60 vs 14.18±4.41)差异无统计学意义(P>0.05)。[结论]全脑放疗对脑转移瘤患者的总体认知功能有损害,但可改善患者PM功能,RM功能无明显影响。
[Objective] To investigate the functional impairment of prospective memory (PM) and retrospective memory (RM) after brain-brain metastases in patients with brain metastases. [Methods] Thirty-four patients with brain metastases were included in this study. MMSE and RM and PM questionnaires were performed at 1 week before and 1 month after radiotherapy. [Results] The MMSE score before and after radiotherapy (27.26 ± 1.86 vs 26.35 ± 1.76) had statistical significance (P <0.05). The PM score after radiotherapy was 12.18 ± 2.74, which was lower than that before radiotherapy (14.06 ± 4.66) (P <0.01). There was no significant difference between the two groups (14.26 ± 4.60 vs 14.18 ± 4.41) before and after radiotherapy (P> 0.05). [Conclusion] Whole brain radiotherapy has a detrimental effect on the overall cognitive function of patients with brain metastases, but can improve the PM function of patients without any significant effect on the function of RM.