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目的探讨无蛋白尿T2DM肾功能异常的影响因素。方法收集尿白蛋白排泄率正常的122例T2DM患者资料。根据肾小球滤过率(GFR)分为肾功能正常组(90例)和异常组(32例),对两组间临床及实验室指标进行比较。结果 Logistic回归分析显示性别、年龄、BMI、糖尿病病程及高血压史是独立相关影响因素。结论针对上述影响因素的综合预防及治疗对延缓肾功能减退有重要意义。
Objective To investigate the influencing factors of renal dysfunction in proteinuria-free T2DM. Methods Data of 122 T2DM patients with normal urinary albumin excretion rate were collected. According to glomerular filtration rate (GFR) were divided into normal renal function group (90 cases) and abnormal group (32 cases), the clinical and laboratory indicators were compared between the two groups. Results Logistic regression analysis showed that gender, age, BMI, duration of diabetes and history of hypertension were independent influencing factors. Conclusion Comprehensive prevention and treatment of the above factors is of great significance for delaying renal dysfunction.