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目的调查青海省海北藏族自治州棘球蚴病的流行分布现状。方法对海北州4县≥3岁当地居民和在校学生采用B超和ELISA法检查棘球蚴感染及患病情况;收集家犬粪便,采用ELISA法检测棘球绦虫抗原;采用病原学方法调查当地家畜和野生啮齿类动物棘球蚴感染情况。结果调查13 241人,B超查出棘球蚴病患者33例(占0.25%),均为囊型棘球蚴病;儿童棘球蚴病患病率为0(0/5 369),细粒棘球蚴抗体阳性率为8.03%(431/5 369)。调查家犬1 259只,粪抗原阳性率为17.8%(231/1 295);调查家畜(牛、羊)和野生啮齿类动物3 043头和4 048只,感染率分别为3.52%(1 07/3 043)和0.86%(35/4 048)。结论海北州为细粒棘球绦虫Ⅱ类流行区,犬是其主要传染源。
Objective To investigate the epidemic distribution of hydatid disease in Haibei Tibetan Autonomous State in Qinghai Province. Methods The echinococcus granulosus infection and its prevalence were examined by using B-ELISA and ELISA method among local residents and school-age students ≥4 years old in 4 counties of Haibei prefecture. The faeces of domestic dogs were collected and the echinococcus antigen was detected by ELISA. Local livestock and wild rodents hydatid infection. Results A total of 13,241 patients were diagnosed by echocardiography, and 33 cases (0.25%) of whom were diagnosed as echinococcosis by cystic duct echinococcosis. The prevalence of hydatidosis was 0 (0/5 369) in children The positive rate of Echinococcus antibody was 8.03% (431/5 369). A total of 1 259 domestic dogs were investigated. The positive rate of fecal antigens was 17.8% (231/1 295). A total of 3 043 and 4 048 domestic animals (cattle and sheep) and wild rodents were investigated. The infection rates were 3.52% / 3 043) and 0.86% (35/4 048). Conclusion Haibei prefecture is the endemic area of Echinococcus granulosus Ⅱ, dogs are the main source of infection.