论文部分内容阅读
目前我国大部分地区对于视网膜母细胞瘤仍采取手术摘除眼球的方法,虽然能提高一部分患儿的生存率,但手术不仅造成患儿生理上的创伤,对儿童将来的健康发展也有深远的心理影响。随着临床研究和治疗技术水平的提高,对患儿生活质量要求也不断提高。眼球摘除、外定向放疗(EBRT)等已不能满足这种要求,化疗联合局部治疗是目前国际上公认的首要治疗方法。同时,对放疗具有指导意义的R-E分级已不适合指导化疗,近年来提出的建立在化疗联合局部治疗基础上的IRC分级,具有非常重要的临床指导意义。(眼科,2007,16:368-372)
At present, the majority of areas in our country still take retinal blastoma surgical excision of the eye, although it can improve the survival rate of some children, but surgery not only causes physical trauma in children, but also have a profound psychological impact on children’s future health development . With the clinical research and treatment technology to improve the quality of life of children also continue to increase. Eye removal, external targeted radiotherapy (EBRT) and so can not meet this requirement, chemotherapy combined with local treatment is currently recognized as the primary treatment. At the same time, R-E grading that is instructive for radiotherapy is not suitable for guiding chemotherapy. In recent years, the IRC classification based on chemotherapy combined with local treatment has very important clinical significance. (Ophthalmology, 2007,16: 368-372)