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目的了解本地区乙型肝炎（ＨＢＶ）母婴传播的现状，评价ＰＣＲ技术的应用价值。方法用ＰＣＲ技术对１５６例孕妇及１１２例新生儿进行了ＨＢＶ检测。结果孕妇ＨＢＶ感染率为１０．２６％，孕妇ＨＢＶ－ＤＮＡ阳性者，其新生儿ＨＢＶ感染率为５６．２５％。结论本地区新生儿ＨＢＶ感染率明显高于国内报道。ＰＣＲ技术用于诊断ＨＢＶ感染简便、快捷、可靠。
Objective To understand the status of mother-to-child transmission of hepatitis B (HBV) in this area and to evaluate the value of PCR technology. Methods HBV was detected in 156 pregnant women and 112 newborns by PCR. Results HBV infection rate in pregnant women was 10.26%. HBV-DNA positive in pregnant women, the neonatal HBV infection rate was 56.25%. Conclusion The HBV infection rate of newborns in this area is obviously higher than that reported in China. PCR technology for the diagnosis of HBV infection is simple, fast and reliable.