由于药物使用造成耳鼻咽喉器官的器质或功能性损害常有发生,其中以耳部的损害对人体影响最为显著,重者致残。早年即有使用土荆芥油驱虫和金鸡钠皮碱治疗疟疾发生耳中毒的报告,有关水杨酸类药物引起耳鸣,耳聋也早有报导。近二、三十年来,随着抗生素的普遍应用,氨基糖苷类抗生索对听力及前庭器官损害的报告大为增多,作者于1964年在开封市作聋人调查中,由于使用链霉索致聋者只占1%,而1986年邓端志报 Due to the use of drugs caused by otolaryngology organs or functional damage often occur, of which the ear damage the most significant impact on the human body, severe disability. Earlier that there are reports of the use of earthworm oil deinsector and goldsmith soda alkali treatment of ototoxicity in malaria, the salicylic acid-induced tinnitus, deafness has long been reported. Nearly two or three decades, with the widespread use of antibiotics, aminoglycoside antibacterial cord hearing and damage of vestibular organs greatly increased the report in 1964 in Kaifeng City for the deaf investigation, due to the use of streptomycin Only 1% of deaf people, while in 1986 Deng Duanzhi newspaper