自1971年Greene将毒扁豆碱用于拮抗术后嗜睡以(?)陆续有人报告,毒扁豆碱可以加快安定、氯胺酮、吗啡、氟烷、神经安定镇痛麻醉(NLA)后的苏醒。随着全麻手术的增多,催醒问题愈来愈受到人们的关注。本文就近年来将毒扁豆碱用于手术麻醉后催醒的情况作一概述。国内在1972年就成功地将毒扁豆碱用于中药麻醉催醒,有关这方面的内容,已有专著论述,本文不再赘述。药理作用毒扁豆碱系一种可逆性胆碱酯酶抑制剂,是从毒扁豆种子中提纯的生物碱,呈碱性,临床应用其水杨酸制剂,可溶于水,本药属叔胺类化合物,其化学结构中的氮原子 Since 1971, Greene has been used to antagonize postoperative sleepiness (?). It has been reported that physostigmine can accelerate the recovery of diazepam after ketamine, morphine, halothane, and neuroleptic analgesia (NLA). With the increase of general anesthesia surgery, wake up more and more people’s attention. This article in recent years, physostigmine anesthesia for the wake of the situation made an overview. Domestic in 1972, the successful use of physostigmine for drug reminder, the content in this regard, monographs have been discussed, this article will not repeat them. Pharmacological action Physostigmine is a reversible cholinesterase inhibitor, which is alkaloid purified from seeds of poisonous lentils. It is alkaline and its application is salicylic acid. It is soluble in water, Class compounds, the nitrogen atoms in their chemical structure