Effects of temperature and pressure differences on water seepage in breccia were investigated by using the physicochemical seepage instrument.The results show that the relationship of flow and pressure differences can be expressed by a linear equation,and the seepage coefficient is linearly correlated with temperature.The relation-ship between seepage flow and temperature could be described with the linear equation.The constant and tempera-ture seepage coefficient showed a linear relation with pressure.Binary quantitative equation for the seepage flow,temperature and pressure was obtained,and explained with experimental data and theoretical analysis. Effects of temperature and pressure differences on water seepage in breccia were investigated by using the physicochemical seepage instrument. The results show that the relationship of flow and pressure differences can be expressed by a linear equation, and the seepage coefficient is linearly correlated with temperature. relation-ship between seepage flow and temperature could be described with the linear equation. constant and tempera-ture seepage coefficient showed a linear relation with pressure. Binary quantitative equation for the seepage flow, temperature and pressure was obtained, and explained with experimental data and theoretical analysis.