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目的 :探讨长期心肌缺血对急性心肌梗塞 (AMI)临床表现与近期预后的影响。方法 : 回顾性分析了 5 96例心绞痛 (AP)病程≥ 2周的 AMI的临床资料 ,并与无 AP史或 AP<2周的患者比较。结果 : AP组合并休克、心衰者少于对照组 (分别为 10 .9%比 15 .8%和 19.8%比 2 5 .0 % ,均 P<0 .0 5 ) ,住院病死率也较低 (11.4%比 15 .7% ,P<0 .0 5 ) ,AP组梗塞前正规治疗者多于对照组 (5 8.4%比 2 9.1% ,P<0 .0 0 1) ,患高血压者也较多(5 3.1%比 41.2 % ,P<0 .0 0 1) ,但大面积梗塞较少 ,肌酸激酶峰值较低。结论 : 长期心肌缺血可能也有缺血预适应作用 ,有益于 AMI的近期预后
Objective: To investigate the effect of long-term myocardial ischemia on the clinical manifestations and immediate prognosis of acute myocardial infarction (AMI). Methods: The clinical data of 5 96 AMI patients with angina pectoris (AP)> 2 weeks were retrospectively analyzed and compared with those without AP history or AP <2 weeks. Results: AP combined with shock and heart failure were less than those in the control group (10.9% vs 15.8% and 19.8% vs 25.0%, respectively, P <0.05) (11.4% vs 15.7%, P <0.05). In the AP group, the number of regular treatment before infarction was more than that of the control group (5 8.4% vs 21.9%, P <0.001) (51.1% vs. 41.2%, P <0.001), but large infarcts were less and peak creatine kinase was lower. CONCLUSION: Long-term myocardial ischemia may also have ischemic preconditioning, which is beneficial to the short-term prognosis of AMI