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目的探讨静脉应用卡贝缩宫素在剖宫产术中对产妇血流动力学的影响。方法选取在连续硬膜外麻醉下行子宫下段剖宫产产妇200例,随机将其分为观察组(K组)与对照组(S组),对照组产妇分娩后静脉滴注缩宫素10 U;观察组产妇分娩后静脉注射卡贝缩宫素100μg,比较两组产妇在给药前和给药后3 min、5 min、10 min观察指标的变化。结果 S组产妇用药后3 min较用药前SBP、DBP明显降低(P<0.05),HR明显增快(P<0.05),而K组无明显变化。结论剖宫产术中静脉应用卡贝缩宫素对产妇的循环系统功能在短时间内无明显的影响。
Objective To investigate the effect of intravenous carbetocin on maternal hemodynamics during cesarean section. Methods 200 cases of cesarean section under continuous uterine epidural anesthesia were randomly divided into observation group (group K) and control group (group S). The control group was given intravenous injection of oxytocin 10 U ; The observation group maternal injection of carbetocin 100μg intravenously after delivery, compared the two groups of maternal before administration and after administration of 3 min, 5 min, 10 min observation index changes. Results The serum levels of SBP and DBP in group S were significantly lower than those before treatment (P <0.05) 3 min after administration, HR was significantly increased (P <0.05), but no significant change was observed in group K. Conclusion Intravenous carbetocin in cesarean section has no obvious effect on maternal circulatory system function in a short period of time.