继发于肝病的神经精神症状群被称为肝昏迷或肝性脑病,而肝性脑病一词能更好地反映这一广泛的神经学方面的紊乱。最近对这种病变的许多方面进行了讨论,这篇综述着重于选择性的临床表现,讨论了病理、发病机理的新观点,并对这种病的治疗现状进行了估价。临床表现肝性脑病病变的临床表现是变化多端的。但一般有三种常见的表现;①脑病可能伴有急性肝病,常为病毒、中毒、或药物所引起的大量肝坏死。在这种情况下,昏迷的产生常常是急剧发生的单发事件,且病程险恶。表现为谵妄,惊厥。偶然还可出现去大脑强直,其结果常常是致命的。②继发于慢性肝病以及门腔系分流术后病人的脑病,大部分昏迷开 The neuropsychiatric syndrome secondary to liver disease is called hepatic coma or hepatic encephalopathy, and the term hepatic encephalopathy better reflects this wide range of neurological disorders. Many aspects of this lesion have recently been discussed. This review focuses on alternative clinical manifestations, discusses new perspectives on pathology and pathogenesis, and evaluates the status of treatment for the disease. Clinical manifestations of hepatic encephalopathy lesions are changing clinical manifestations. But generally there are three common manifestations; ① encephalopathy may be associated with acute liver disease, often caused by viruses, poisoning, or drugs caused by a large number of liver necrosis. In this case, coma is often a single episode of rapid onset, and the course of the sinister. Showed as delirium, convulsions. Occasionally there may be to go to brain rigidity, the result is often fatal. ② secondary to chronic liver disease and portal system shunt patients with encephalopathy, most of the coma