HLA分子是免疫应答过程中的重要分子 ,其表达受到多种因素的影响。调控HLA基因表达的主要环节在转录水平 ,转录起始点上游 2 5 0bp中顺式作用元件和反式作用因子的相互作用是影响HLA基因转录的重要因素。了解HLA分子表达的复杂调控机制在免疫学中有着重要的理论和实用价值 HLA molecules are important molecules in the process of immune response, and their expression is affected by many factors. The main part of the regulation of HLA gene expression is at transcriptional level. The interaction of cis-acting elements and trans-acting factors upstream of transcription start point is an important factor affecting HLA gene transcription. Understanding the complex regulatory mechanisms of HLA molecular expression has important theoretical and practical values ​​in immunology