本文介绍一种新型的头部含抗菌素的硅橡胶导尿管。该管药头部应用单组份硫化硅橡胶和硫酸卡那霉素,按1:1混合在室温下固化制成。每个药头含硫酸卡那霉素20～30万单位。体外测试证实能释放有效抑菌浓度(>20单位/毫升),持续20天左右。临床试用28例的资料表明应用该管后尿内白细胞明显减少。17例测定尿内卡那霉素,有15例大于20单位/毫升,12例使用该管前尿培养阳性者中有10例复查尿培养,结果有8例转为阴性。 This article describes a new type of head containing antibiotic silicone rubber catheter. The pipette head application of one-component silicone rubber and kanamycin sulfate, according to 1: 1 mixed at room temperature curing made. Each drug contains kanamycin sulfate 20 to 300,000 units. In vitro tests confirmed the release of effective inhibitory concentrations (> 20 units / ml) for about 20 days. Clinical trial of 28 cases of data show that the use of the tube after urinary white blood cells decreased significantly. 17 cases of determination of kanamycin in the urine, 15 cases were greater than 20 units / ml, 12 cases of urine culture before using this tube, 10 cases of urine culture review, the results of 8 cases turned negative.