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目的:探索颅内动脉瘤不同时机血管内介入治疗的临床疗效,以期为临床实践提供参考。方法:采取回顾性分析的方法,选取我院于2014年6月至2015年7月间收治的150例颅内动脉瘤破裂后行血管介入栓塞术患者作为临床研究对象,对其临床资料进行回顾性分析。结果:经统计发现,早期组患者二次出血、脑血管痉挛以及脑积水等并发症的发病率明显低于中期组和晚期组(P<0.05),差异具有统计学意义;中期组和晚期组相比较而言,前者发病率虽然高于后者,但两组差异不明显(P>0.05),无统计学意义。GOS评分发现,颅内动脉瘤行血管内介入栓塞术中期组预后良好率为67.4%(29/43),相比于晚期组预后良好率66.1%(41/62),两组差异不明显(P>0.05),不具有统计学意义。结论:颅内动脉瘤破裂后行血管内介入栓塞术在早期和中期治疗效果较佳,晚期二次出血发生率明显高于中期和早期,后者之间无显著性差异。因此,在中期尽可能早的对患者实施动脉瘤栓塞术有助于避免动脉瘤二次破裂,但中期和晚期预后无显著性差异。
Objective: To explore the clinical effect of intracranial interventional therapy of intracranial aneurysm with different timing, in order to provide reference for clinical practice. Methods: A retrospective analysis method was used to select 150 patients with ruptured intracranial aneurysms who underwent vascular embolization in our hospital from June 2014 to July 2015 as the clinical study subjects, and their clinical data were reviewed Sexual analysis. Results: The incidences of complications such as secondary hemorrhage, cerebral vasospasm and hydrocephalus in the early group were significantly lower than those in the intermediate group and the late group (P <0.05), and the difference was statistically significant. In the intermediate group and the late group Compared with the control group, the incidence of the former is higher than the latter, but there is no significant difference between the two groups (P> 0.05). There is no statistical significance. The GOS score showed that the good prognosis of the intracranial aneurysm in the interim embolization group was 67.4% (29/43), compared with 66.1% (41/62) in the advanced group, the difference was not significant P> 0.05), not statistically significant. Conclusion: Endovascular interventional embolization after intracranial aneurysm rupture is better in the early and middle stages of treatment, the incidence of late secondary hemorrhage is significantly higher than that in the middle and early stages, there is no significant difference between the latter. Therefore, performing aneurysm embolization in patients as early as possible in the mid-term may help prevent aneurysm secondary rupture, but there is no significant difference in metaphase and late prognosis.