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目的:本次研究使用一种数学方法将静脉血气转化以得到与动脉血气类似的结果,在30例急诊哮喘患者中研究这一方法的准确性。方法:30例急诊哮喘患者入院后5min内于同一侧肢体采集动、静脉血标本,记录指脉氧饱和度,分别观察静脉血气、动脉血气和经过转化后的静脉血气pH值、PO2、PCO2的关系。结果:静脉血和动脉血比较,pH、PCO2、PO2相关性较好,r2分别为0.94、0.82、0.73,Bland-Altman法分析后偏倚和标准差分别为0.038±0.055,-1.41±1.48,3.13±2.02,均超过实验室可接受的误差范围。经过数学方法转化后的静脉血与动脉血指标比较,pH、PCO2、PO2相关性较好,r2分别为0.97、0.98、0.85,Bland-Altman法得出偏倚和标准差分别为-0.01±0.04,0.05±0.39,1.36±1.57,其中pH、PCO2在实验室可以接受的误差范围内,PO2超出了实验室可接受的误差范围。结论:静脉血气与动脉血气结果差异较大,通过数学方法转化的静脉血气可以提供与动脉血气类似的pH和PCO2结果,但PO2结果与动脉血气结果相差较大,需要进一步改进方法研究。
OBJECTIVE: This study used a mathematical approach to convert venous blood gas to obtain similar results as arterial blood gas, and the accuracy of this method was studied in 30 emergency asthma patients. Methods: Thirty patients with acute asthma were collected on the same limbs within 5 minutes after admission to collect the arterial and venous blood samples. The venous blood samples were recorded. The venous blood gas, arterial blood gas and venous blood pH values after the conversion were observed. The values of PO2 and PCO2 relationship. Results: The correlations of pH, PCO2 and PO2 in venous blood and arterial blood were good, with r2 values of 0.94, 0.82 and 0.73 respectively. The post-analysis bias and standard deviation of Bland-Altman method were 0.038 ± 0.055, -1.41 ± 1.48, 3.13 ± 2.02, all exceeding laboratory acceptable error range. After the mathematical method of conversion of venous blood and arterial blood indicators, pH, PCO2, PO2 correlation is good, r2 were 0.97,0.98,0.85, Bland-Altman method to obtain the bias and standard deviation were -0.01 ± 0.04, 0.05 ± 0.39,1.36 ± 1.57, where pH and PCO2 were within the laboratory acceptable error range, and PO2 exceeded the laboratory acceptable error range. CONCLUSION: The results of venous blood gas and arterial blood gas differ greatly. Venous blood gas converted by mathematical method can provide similar results of arterial blood gas and PCO2. However, there is a big difference between the results of PO2 and arterial blood gas, which needs further improvement research.