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目的观察散瘀消肿膏对动物皮肤的毒性作用。方法用健康家兔进行皮肤刺激性试验;采用健康大白鼠进行皮肤急性毒性试验;用健康豚鼠进行皮肤过敏试验。结果散瘀消肿膏对家兔完整皮肤和破损皮肤均无刺激性,对大鼠完整皮肤及破损皮肤无皮肤急性吸收毒性,对豚鼠完整皮肤无致敏作用。结论散瘀消肿膏用于活血、化瘀、消肿、止痛是安全无毒的。
Objective To observe the toxic effects of Sanyu Xiaoying Ointment on animal skin. Methods Healthy rabbits were used for skin irritation test. Healthy rats were used for acute skin toxicity test. Healthy guinea pigs were used for skin allergy test. Results: Sanyu Xiaomao Ointment had no irritation to intact skin and damaged skin of rabbits. It had no acute skin absorption toxicity to rat intact skin and damaged skin, and had no sensitization effect on intact skin of guinea pigs. Conclusion Sanyu Xiaoying ointment is safe and non-toxic for blood circulation, phlegm, swelling and pain relief.