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目的：探讨乙炔雌二醇／醋酸环丙孕酮组合剂（达英-35）对多囊卵巢综合征（PCOS）的治疗效果。方法：对未婚和已婚而一年内暂不想生育的52例PCOS患者采用达英-35治疗6个周期，分别于治疗前期第3、6周期末评估临床表现改变和规定血清内分泌指标的变化情况。结呆：治疗3个周期后所有患者月经周期变规则，经量正常，促卵泡激素较治疗前明显下降（P＜0．05），而黄体生成素和睾酮的水平下降更为显著（P＜0．01）；治疗6个周期后痤疮明显改善，但多毛无改变，血清内分泌指标与第3周期末比较均无显著性改变（P＞0．05）。结论：短期使用达英-35能明显改善其典型的内分泌紊乱，控制规则的月经周期。
Objective: To investigate the therapeutic effect of ethinyl estradiol / cyproterone acetate combination (Da Ying-35) on polycystic ovary syndrome (PCOS). Methods: Fifty-two PCOS patients who did not want to give birth within one year were enrolled in this study. Six cycles of up to -35 treatment were performed. Changes in clinical manifestations and changes of serum endocrine indexes were evaluated at the end of the third and sixth cycles . Results: After treatment for 3 cycles, all patients had regular menstrual cycles, normal menstruation, follicle-stimulating hormone decreased significantly (P <0.05), and the levels of luteinizing hormone and testosterone decreased more significantly (P < 0.01). Acne was significantly improved after 6 cycles, but hirsutism did not change. Serum endocrine index had no significant change compared with the end of the third cycle (P> 0.05). Conclusion: Short-term use of da-Ying-35 can significantly improve its typical endocrine disorders, control the rules of the menstrual cycle.