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目的:观察平消胶囊联合常规放化疗治疗肺癌的疗效及副作用。方法:选取中晚期肺癌患者80例,采用随机数字对照表法将患者分为2组各40例,对照组行常规化疗,观察组在对照组治疗方案的基础上予以平消胶囊治疗,评估临床疗效及毒副作用,观察治疗前后免疫功能的变化情况。结果:观察组治疗有效率87.5%,高于对照组67.5%,差异有统计学意义(P<0.05);观察组Ⅱ~Ⅳ级白细胞减少、血小板下降、骨髓抑制发病率分别为7.5%、12.5%、7.5%,低于对照组35.0%、32.5%、32.5%,差异均有统计学意义(P<0.05);观察组治疗后CD3~+、CD4~+、CD4~+/CD8~+高于对照组,差异均有统计学意义(P<0.05)。结论:平消胶囊联合常规放化疗治疗肺癌可提高机体免疫功能,减轻化疗毒副反应,提高化疗效果。
Objective: To observe the curative effect and side effects of Pingxiao capsule combined with conventional radiotherapy and chemotherapy for lung cancer. Methods: Eighty patients with advanced lung cancer were selected. Patients were divided into two groups (n = 40) by random number table. The control group received routine chemotherapy. The observation group was treated with Pingxiao capsule based on the control group’s treatment plan, and the clinical Efficacy and side effects, observed changes in immune function before and after treatment. Results: The effective rate of observation group was 87.5%, higher than 67.5% of control group, the difference was statistically significant (P <0.05); the observation group Ⅱ ~ Ⅳ grade leukopenia, thrombocytopenia, myelosuppression rates were 7.5%, 12.5 %, 7.5%, lower than the control group 35.0%, 32.5%, 32.5%, the difference was statistically significant (P <0.05); after treatment, the levels of CD3 +, CD4 +, CD4 + / CD8 + In the control group, the differences were statistically significant (P <0.05). Conclusion: Pingxiao capsule combined with conventional radiotherapy and chemotherapy for lung cancer can improve immune function, reduce chemotherapy side effects and improve the effect of chemotherapy.