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血管紧张素转换酶2(angiotensin converting en-zyme type2,ACE2)是脑肾素血管紧张素系统的新成员,在肾素血管紧张素系统过度活跃时可能被激活。该文探索了中枢ACE2的作用,应用一种新的转基因小鼠模型,该模型在小鼠中转入由突触蛋白(synapsin)启动子调控的人类ACE2(human ACE2,
Angiotensin converting en-zyme type 2 (ACE2) is a new member of the renin-angiotensin system that may be activated when the renin-angiotensin system is hyperactive. This study explored the role of central ACE2 in the development of a novel transgenic mouse model that was transfected in mice into human ACE2 (human ACE2) cells regulated by the synapsin promoter