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目的:检测分析重症急性胰腺炎(SAP)患者血清降钙素原(PCT)和C-反应蛋白(CRP)水平及临床意义。方法:72例确诊为SAP患者为实验组,其中合并感染者(SAP感染组)34人,未合并感染者(SAP未感染组)38人;另选60名健康体检者为对照组。分别检测比较各组血清PCT和CRP水平差异。结果:实验组中合并感染者和未合并感染者的PCT和CRP水平均高于对照组,差异有统计学意义(P<0.05);SAP感染组患者CRP和PCT水平均比SAP未感染组增高,差异亦有统计学意义(P<0.05)。结论:PCT和CRP可以作为SAP患者的常规检查指标,早期监测是否并发感染,为SAP患者病情判断及疗效观察提供参考。
Objective: To detect and analyze the serum levels of procalcitonin (PCT) and C-reactive protein (CRP) in patients with severe acute pancreatitis (SAP) and its clinical significance. Methods: Seventy-two patients diagnosed as SAP were selected as the experimental group. Among them, 34 patients were infected with SAP (SAP infected group) and 38 were uninfected (SAP uninfected group). Another 60 healthy subjects were selected as the control group. The levels of serum PCT and CRP in each group were detected and compared. Results: The PCT and CRP levels in experimental group were significantly higher than those in control group (P <0.05). The levels of CRP and PCT in SAP group were significantly higher than those in non-infected group , The difference was also statistically significant (P <0.05). Conclusions: PCT and CRP can be used as routine examination indicators in patients with SAP, early detection of concurrent infection, for the judgment of patients with SAP and the efficacy of treatment to provide a reference.