低肾素低醛固酮综合症(the Syndro-me of hyporeninemic hypoaldosteron-ism,SHH)是由于糖尿病、肾脏疾病或其它原因引起肾素缺乏,血管紧张素Ⅱ(ATⅡ)合成减少或肾上腺球状带萎缩,导致醛固酮分泌降低;部分病人可能有醛固酮合成酶缺陷。临床主要表现高血钾、钠丢失、轻度代谢性酸中毒,常伴有轻度或中度肾功能 The Syndro-me of hyporeninemic hypoaldosteron-ism (SHH) is a cause of renin deficiency, decreased synthesis of angiotensin II (AT II), or atrophy of the adrenal bulb due to diabetes mellitus, kidney disease or other causes Aldosterone secretion decreased; some patients may have aldosterone synthase defects. The main clinical manifestations of hyperkalemia, sodium loss, mild metabolic acidosis, often accompanied by mild or moderate renal function