白细胞介素-1(IL-1) 被视为宿主对感染反应的关键性的先导物。严重感染时监测IL-1有助于预后判断。病例例1:7岁,男,既往体健。因上呼吸道感发热1天,体温40.2℃,半天来病情加重,伴抽搐15分,经直肠给安定后转入院。查体:热性重病容,神志不清,对静脉穿刺有缩手反应。脑脊液(CSF)混浊,白细胞15.5×10~9/L,多形核99%,葡萄糖 Interleukin-1 (IL-1) is considered as a key lead in host response to infection. Monitoring IL-1 during severe infections can help predict prognosis. Case 1: 7 years old, male, past physical health. Fever due to upper respiratory tract sensitization 1 day, body temperature 40.2 ℃, half a day to aggravate the condition, with convulsions 15 minutes, transrectal to diazepam after admission. Physical examination: Severe febrile illness, confusion, venous puncture shrinkage response. Cerebrospinal fluid (CSF) turbidity, white blood cells 15.5 × 10 ~ 9 / L, polymorphonuclear 99%, glucose