我们对52例急性白血病(AL)患者共81次脑脊液β_2-微球蛋白(CSFβ_2-M)的测定,发现其对中枢神经系统白血病(CNSL)的早期诊断和病情监测具有肯定的意义。临床资料①正常对照组27例,年龄20～50岁,均为非神经系统及非肿瘤外科患者术前腰麻时留取脑脊液标本。②AL组(含13例CNSL),年龄8～65岁,其中急性淋巴细胞白血病(ALL)34例,急性非淋巴细胞白血病(ANLL)18例。③合并CNSL13例,其中ALL8例,ANLL5例。采用放射免疫法测定CSFβ_2-M,结果见附表。 We measured a total of 81 cerebrospinal fluid β2-microglobulin (CSFβ_2-M) in 52 patients with acute leukemia (AL) and found that it has positive significance in the early diagnosis and condition monitoring of central nervous system leukemia (CNSL). Clinical data ① 27 cases of normal control group, aged 20 to 50 years, were non-neurological and non-surgical patients with spinal surgery before surgery to retain cerebrospinal fluid samples. ② The AL group (including 13 CNSL), aged 8 to 65 years old, including 34 cases of acute lymphoblastic leukemia (ALL) and 18 cases of acute non-lymphocytic leukemia (ANLL). ③ combined CNSL13 cases, including ALL8 cases, ANLL5 cases. CSFβ2-M was determined by radioimmunoassay. The results are shown in the attached table.