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目的 :探讨结核感染T细胞斑点试验在诊断慢性阻塞性肺疾病(COPD)伴肺结核患者中的临床价值。方法 :回顾性分析我院2013年6月到2014年12月收治的90例COPD疑似肺结核患者,所有患者采用结核感染T细胞斑点试验(T-SPOT.TB)进行检测,并同时采用结核菌素试验(PPD)进行对比分析。结果 :T-SPOT.TB试验的灵敏度为79.07%,特异度为87.23%,假阳性率为12.24%,假阴性率为20.93%。T-SPOT.TB试验的阳性检出率为79.07%,PPD试验的阳性检出率为48.84%。两组相比较,T-SPOT.TB试验的阳性检出率显著高于PPD试验。结论:T-SPOT.TB试验诊断COPD伴结核的灵敏度、特异性、准确率高,值得临床推广应用。
Objective: To investigate the clinical value of T-cell stain test of tuberculosis infection in the diagnosis of patients with chronic obstructive pulmonary disease (COPD) and pulmonary tuberculosis. Methods: A total of 90 COPD patients with suspected pulmonary tuberculosis who were admitted to our hospital from June 2013 to December 2014 were retrospectively analyzed. All patients were tested by T-SPOT.TB. Toxins tuberculosis Test (PPD) for comparative analysis. Results: The sensitivity of T-SPOT.TB test was 79.07%, the specificity was 87.23%, the false positive rate was 12.24% and the false negative rate was 20.93%. The positive detection rate of T-SPOT.TB test was 79.07%, and the positive detection rate of PPD test was 48.84%. Compared with the two groups, the positive detection rate of T-SPOT.TB test was significantly higher than PPD test. Conclusion: The sensitivity, specificity and accuracy of T-SPOT.TB test in diagnosis of COPD with tuberculosis are worthy of clinical application.