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四环素类一、四环素类与制酸药当四环素类(TC)药物与铝(Al)、镁(Mg)、钙(Ca)化合物一起应用时,两者能形成络合物,从而变成经肠道难以吸收的化合物(图1)。因此,对应用四环素类的病人,在消化道障碍而考虑给予制酸药时,必须对上述情况引起注意。即使四环素类与含钙(Ca)的牛奶、乳制品等食品并用,也能引起四环素类药物吸收的障碍。另外,即使四环素与不属于制酸药的铋(Bi)化合物并用时,同样能引起四环素类吸收的障碍。
Tetracyclines Tetracyclines and Antacids When tetracycline (TC) drugs are used in combination with aluminum (Al), magnesium (Mg), calcium (Ca) compounds, the two form complexes and thus become enteral Road difficult to absorb compounds (Figure 1). Therefore, the application of tetracyclines in patients with gastrointestinal disorders and considering the antacids given, we must pay attention to the above situation. Even tetracycline and calcium (Ca) milk, dairy products and other foods used, but also cause tetracycline drug absorption barriers. In addition, even when tetracycline is used in combination with a bismuth (Bi) compound that is not an antacid, tetracycline-like absorption can also be caused.