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目的:观察艾灸足三里、神阙穴配合格拉司琼对肠道肿瘤患者接受铂类化疗所致消化道副反应的疗效。方法:随机将69例在我科欲行含铂类方案化疗的恶性肠道肿瘤患者分为对照组与观察组,对照组34例和治疗组35例。对照组34例仅用格拉司琼针静脉注射。治疗组35例在此基础上加用艾灸足三里、神阙穴,各10~15min,并且,在进行治疗后的30min~60min观察临床效果。结果:配合使用艾灸治疗的恶性肠道肿瘤化疗患者,患者的恶心呕吐分级较单纯使用格拉司琼防治呕吐的患者要轻,差异具有显著性意义(P<0.05)。结论:艾灸足三里、神阙穴配合格拉司琼能有效减轻恶性肠道肿瘤患者接受铂类化疗方案所致恶心呕吐反应。
Objective: To observe the effect of moxibustion Zusanli and Shenque acupoints combined with granisetron on gastrointestinal side effects caused by platinum-based chemotherapy in patients with intestinal cancer. Methods: Sixty-nine patients with malignant intestinal tumors who were treated with platinum-containing chemotherapy were randomly divided into control group and observation group, 34 cases in control group and 35 cases in treatment group. Control group 34 patients received intravenous granisetron only. 35 cases in the treatment group were given moxibustion Zusanli and Shenque acupoints on the basis of 10-15 minutes each, and the clinical effect was observed 30min ~ 60min after the treatment. Results: In patients with malignant intestinal tumor treated with moxibustion, the grade of nausea and vomiting was lighter in patients treated with granisetron than vomiting alone, the difference was significant (P <0.05). Conclusion: Moxibustion at Zusanli and Shenque acupoints with granisetron can effectively reduce nausea and vomiting induced by platinum-based chemotherapy in patients with malignant intestinal tumors.