放疗联合基因治疗恶性肿瘤的研究正日益受到重视 ,实验显示放疗联合基因治疗肿瘤二者有明显的协同作用 ,能有效提高对肿瘤细胞的杀伤效能。本文对 CD基因的作用机理、CD基因的靶向转移、放射线联合 CD基因治疗结直肠癌等方面的研究进行综述 Radiotherapy combined with gene therapy for malignant tumors are increasingly valued. Experiments show that radiotherapy combined with gene therapy has obvious synergistic effects on both tumors, which can effectively improve the killing effect on tumor cells. This review summarizes the mechanism of action of CD gene, target gene transfer of CD gene and radiation therapy combined with CD gene in colorectal cancer